Declining tempting offers from medical schools in Missouri and Tennessee, he, in 1852, resigned his chair in Philadelphia and accepted that of Theory and Practice of Medicine in the Kentucky School of Medicine at Louisville. He performed the duties of that professorship to the satisfaction of all parties until 1854, when he resigned on account of ill health and returned to his native city. Recovering, in a measure, his health, he was chosen, without any movement on his part, to fill the chair of Materia Medica and General Therapeutics in Jefferson Medical School of Philadelphia. This chair he occupied up to the year of his death. Doctor Mitchell was an able and indefatigable writer and author. Without recurring to his earlier writings, he published in 1832 an octavo volume of five hundred and fifty-three pages, _On Chemical Philosophy_, on the basis of _The Elements of Chemistry_, by Doctor Reid, of Edinburgh. In the same year he produced his _Hints to Students_, and acted as co-editor of the _Western Medical Gazette_ with Professors Eberle and Staughton; contributed papers to the _New York Repository_, _Philadelphia Museum_, _Western Journal of Medicine and Surgery_, _Western Medical Recorder_, _Western Lancet_, _American Medical Recorder_, _American Review_, _North American Medical and Surgical Journal_, _Transylvania Medical Journal_,[82] _New Orleans Medical and Surgical Journal_, _Esculapian Register_, etc. In 1850, he published an octavo volume of seven hundred and fifty pages _On Materia Medica_, also an edition of _Eberle on the Diseases of Children_, to which he added notes and a sequel of some two hundred pages. He also wrote a volume of six hundred pages _On the Fevers of the United States_, which he did not publish. Doctor Mitchell was a clear and impressive lecturer, a most industrious student even in his latter days, a learned, classical, and scientific scholar and a most rigidly upright and conscientious gentleman.[83] JAMES MILLS BUSH, M. D., A native of Kentucky,[84] born in Frankfort May, 1808, graduated as A. B. in Centre College, Danville, Kentucky, and began the study of medicine and surgery in the office of the celebrated Doctor Alban Goldsmith, Louisville, Kentucky. He removed to Lexington in 1830-31, to attend the medical lectures in Transylvania University, and to become a private pupil of its renowned surgeon, Professor Benjamin W. Dudley. To Doctor Dudley he became personally attached by sentiments of affection and esteem, which were warmly returned by his eminent preceptor; so that, when young Bush received the honor of the degree of Doctor of Medicine in 1833, Doctor Dudley immediately appointed him his demonstrator and prosector in Anatomy and Surgery, to which branches of medical science and art Doctor Bush was ardently devoted.