"A most remarkable feature in the bite of the Tsetse is its perfect harmlessness in man and wild animals, and even calves so long as they continue to suck the cows. We never experienced the slightest injury from them ourselves personally, although we lived two months in their habitat, which was in this case as sharply defined as in many others, for the south bank of the Chobe was infested by them, and the northern bank, where our cattle were placed, only fifty yards distant, contained not a single specimen. This was the more remarkable, as we often saw natives carrying over raw meat to the opposite bank with many Tsetses settled on it. "The poison does not seem to be injected by a sting, or by ova placed beneath the skin, for, when one is allowed to feed freely on the hand, it is seen to insert the middle prong of three portions, into which the proboscis divides, somewhat deeply, into the true skin. It then draws it out a little way, and it assumes a crimson colour, as the mandibles come into brisk operation. The previously-shrunken belly swells out, and, if left undisturbed, the fly quietly departs when it is full. A slight itching irritation follows, but not more than in the bite of the mosquito. In the ox this same bite produces no more immediate effects than in man. It does not startle him, as the gad-fly does; but a few days afterwards the following symptoms supervene: the eyes and nose begin to run, the coat stares as if the animal were cold, a swelling appears under the jaw, and sometimes on the navel; and, though the animal continues to graze, emaciation commences, accompanied with a peculiar flaccidity of the muscles, and this proceeds unchecked until, perhaps months afterwards, purging comes on, and the animal, no longer able to graze, perishes in the state of extreme exhaustion. Those which are in good condition often perish, soon after the bite is inflicted, with staggering and blindness, as if the brain were affected by it. Sudden changes of temperature produced by falls of rain seem to hasten the progress of the complaint; but in general the emaciation goes on uninterruptedly for months, and, do what we will, the poor animals perish miserably.