It is so long since I first took opium, that if it had been a trifling incident in my life I might have forgotten its date; but cardinal events are not to be forgotten; and, from circumstances connected with it, I remember that it must be referred to the autumn of 1804. During that season I was in London, having come thither for the first time since my entrance at college. And my introduction to opium arose in the following way: From an early age I had been accustomed to wash my head in cold water at least once a day. Being suddenly seized with toothache, I attributed it to some relaxation caused by an accidental intermission of that practice; jumped out of bed, plunged my head into a basin of cold water, and with hair thus wetted went to sleep. The next morning, as I need hardly say, I awoke with excruciating rheumatic pains of the head and face, from which I had hardly any respite for about twenty days. On the twenty-first day I think it was, and on a Sunday, that I went out into the streets; rather to run away, if possible, from my torments than with any distinct purpose. By accident I met a college acquaintance, who recommended opium. Opium! dread agent of unimaginable pleasure and pain! I had heard of it as I had heard of manna or of ambrosia, but no further. How unmeaning a sound it was at that time! what solemn chords does it now strike upon my heart! what heart-quaking vibrations of sad and happy remembrances! It was a Sunday afternoon, wet and cheerless; and a duller spectacle this earth of ours has not to show than a rainy Sunday in London. My road homeward lay through Oxford Street, and near the "Pantheon" I saw a druggist's shop. The druggist (unconscious minister of celestial pleasures!), as if in sympathy with the rainy Sunday, looked dull and stupid, just as any mortal druggist might be expected to look on a Sunday, and when I asked for the tincture of opium he gave it to me as any other man might do; and furthermore, out of my shilling returned to me what seemed to be a real copper half-penny, taken out of a real wooden drawer. Nevertheless, in spite of such indications of humanity, he has ever since existed in my mind as a beatific vision of an immortal druggist sent down to earth on a special mission to myself.