If the Climate already exerted such an influence on the aboriginal inhabitants, how much greater must this have been where foreigners were concerned, on whom all endemic excitants of disease in a country notoriously work with augmented virulence. In Antiquity this fact must have been even more conspicuously true, inasmuch as at that period the Nations still remained much more unmixed than they subsequently became. It is a thing which always hitherto, speaking generally, has been far too little taken account of by Pathologists, but which is surely of vast importance in connection with the rise and spread of Venereal disease,—without its being in any way implied that we must necessarily therefore adopt the theory of its American origin[160]. If we are not much mistaken, this factor was operative also in the case of the Plague of Baal-Peor. Now what holds good for the Jews, must equally hold good for the other peoples of Asia and of Egypt, and even in an enhanced degree, since these, as we have seen above, gave way to vicious indulgence to a yet more excessive degree. Nevertheless, then as now distinctions no doubt existed, and probably in Antiquity as at the present day there were districts, whose physical conditions of climate might be regarded as actually forming a counteracting factor, and where in spite of excesses the genital organs seldom became diseased. The evidence for this must be given by later investigations, for we must of necessity first possess a geographical Nosology of Venereal disease at the present day, if we are ever to succeed in finding and utilizing the materials for the same in Antiquity. What has been so far collected by the meritorious _Schnurrer_ in his Geographical Nosology is too incomplete to justify us at present in drawing any certain conclusions, more particularly as the greatest part of the material contributed by him is drawn from the communications of non-medical enquirers.