I saw her next morning at a house to which she had been removed at a small distance, and found her almost free from complaints; she had rested moderately well, and was perfectly sensible. Those about her dated her amendment from the time when the purge (which had procured three stools) began to operate. She was however extremely full all over of a very small confluent kind; yet these inflamed and maturated in a very favourable manner. From the minutest observation I could make, it seemed to me that by this management the number in the face was less than when I first saw her, consequently that some pustules were repressed after they had appeared. CASE XXVII. In the beginning of June 1766, a young woman was taken with a shivering fit, succeeded by a fever, and the symptoms that usually precede the small-pox, in a very violent degree: these were attended with such general weakness, that in a few hours after the seizure she was obliged to go to bed, where she soon became delirious, and afterwards insensible, her urine passing involuntarily; in this condition I first saw her about forty hours after she was taken ill. The heat was excessive, her pulse extremely quick, but not strong, and a few small eruptions appeared on the face, sufficient to ascertain the distemper. Upon raising her up she did not make the least effort to support herself, and therefore was permitted to lie down, and as the room was small, the window was set open. Five grs. of calomel were with great difficulty got down; and an infusion of sena and manna being prepared, the person attending was desired to give a little and often, till she had a stool. It was very improper that she should remain in the house where she was, on account of the family; yet there was no possibility of moving her in her present condition. Next morning I was informed she had remained in the same stupid way the whole night, but was now rather better, and had spoke more sensibly, had two stools, and vomited up some bilious matter. The heat was still great, the pulse quick, and many small confluent pustules were out on the face and other parts: this was the third day of her illness. I advised her being got out of bed, and the windows to be kept open; but was in doubt whether she had strength enough to be taken into the open air. In the evening the eruption was increased considerably in number; and she was so much eased of her complaints, as to bear being removed in a cart to a house in the neighbourhood, where I gave her calomel three grains, emetic tartar one eighth of a grain. She had some rest this night, but the fever continued; and not having had any more stools, she was ordered to take a laxative potion of inf. of sena and manna. She had three stools before evening, and all her complaints abated. She was very full all over of a very confluent kind.