_Hair, Epidermis and Glands._--These are all derived from the epithelial layer, and hence, as might be inferred, have much in common in their chemical constitution. They are all classed by chemists under one name, “keratin,” or horny tissue, and their ultimate analysis shows that in elementary composition they closely resemble the albumins. It is evident, however, that the horny tissues are a class rather than a single compound. The keratins are gradually loosened by prolonged soaking in water, and, by continued boiling in a Papin’s digester at 160° C., evolve sulphuretted hydrogen, at the same time dissolving to a turbid solution which does not gelatinise on cooling. Keratin is dissolved by caustic alkalies; the epidermis and the softer horny tissues are easily attacked, while hair and horn require strong solutions and the aid of heat to effect complete solution. The caustic alkaline earths act in the same manner as dilute alkaline solutions; hence lime easily attacks the epidermis, and loosens the hair, but does not readily destroy the latter. Alkaline sulphides, on the other hand, seem to attack the harder tissues with at least the same facility as the soft ones, the hair being often completely disintegrated, while the epidermis is still almost intact; hence their applicability to unhairing by destruction of the hair. Keratins give the xanthoproteic reaction with nitric acid, and a red coloration with Millon’s reagent, and also resemble albumin, in the fact that they are precipitated from their solution in sulphuric acid by potassium ferrocyanide. By fusion with potash, or prolonged boiling with dilute sulphuric acid, keratin is decomposed, yielding leucin, tyrosin, ammonia, etc. The precipitate produced by the addition of acids to alkaline solution of keratin (hair, horns, etc.), mixed with oil and barium sulphate, has been employed by Dr. Putz as a filling material for leather, for which purpose it acts in the same way as the egg-yolks and flour used in kid-leather manufacture. Eitner attempted to use it for the same purpose with bark-tanned leather, but without much success. Putz has also proposed to precipitate the material after first working its solution into the pores of the leather. _Elastic Fibres._--The elastic or yellow fibres of the hide are of a very stable character. They are not completely dissolved even by prolonged boiling, and acetic acid and hot solutions of caustic alkalies scarcely attack them. They do not appear to combine with tannin, and are very little changed in the tanning process. They are present in hide and skin to the extent of less than one per cent. _Analytical Methods._--The reactions distinguishing the principal skin constituents are summarised in the following table:--