Report of the Council on Pharmacy and Chemistry The Waterbury Chemical Company having requested that the Council reconsider its action of four years ago (see preceding report) on the product then known as Waterbury’s Cod-Liver Oil Compound, now called Waterbury’s Compound, the matter was submitted to a referee. The referee reported that the statement now made as to the composition of this product is as follows: “Made from Cod Liver Oil, Digestive Ferments, Malt Extract Unfermented, Hypophosphites Comp. Special, Ext. Cherry, Eucalyptus, Aromatics, etc.” He held that the Waterbury Chemical Company has not submitted satisfactory evidence to indicate that the objections of the Council’s former unfavorable report have been met; that there is no evidence that the product is a substitute for cod-liver oil in any way; and that under the present methods of exploitation it constitutes what is at least an inferential fraud; and recommended that no further consideration be given to Waterbury’s Compound. The report was adopted by the Council.--(_From The Journal A. M. A., March 20, 1915._) COLCHI-SAL Report of the Council on Pharmacy and Chemistry Colchi-Sal, said to be made by the Anglo-American Pharmaceutical Co., Ltd., New York, is advertised, sold and “guaranteed” (sic) by E. Fougera and Co., Inc., New York. According to the label of a recently purchased specimen: “Each Capsule contains Cannabis Indica (Active Principle of) 1-500th Grain (1/8 Milligram); Colchicine (Crystallized) 1-250th Grain (1/4 Milligram); Methyl Salicylate 20 Centigrams.” The advertising circular around the bottle adds that the mixture also contains “appropriate aromatic adjuvants.” It is recommended in “Gouty and Chronic Rheumatic Manifestations,” “acute cases of Gout,” “intestinal auto-intoxication or dyspepsia,” “bilious headaches,” etc. Salicylates are generally recognized as valuable in acute manifestations of acute articular rheumatism; colchicum is useless in these conditions. Both salicylates and colchicum are practically useless in chronic rheumatic and in chronic gouty affections. For dyspepsia, bilious headache, etc., salicylates are distinctly contra-indicated and the drastic purgation produced by colchicum would not be thought desirable. Though methyl salicylate administered internally is not generally considered so efficient as sodium salicylate, it is asserted that the former “... is found far more effective than salicylate of soda or other salicylic derivatives when given in conjunction with colchicine as Colchi-Sal.” Further, the highly improbable and unsubstantiated claim is made that “the active principle of _Cannabis indica_” (whatever that may be) “corrects any tendency of the colchicine to irritate the gastro-intestinal tract” and that the “appropriate aromatic adjuvants” “prevent intolerance of the methyl salicylate.”