Of Italy I can but afford to say generally, that except at a very few points where the Alps or Apennines reach the sea, the whole of its shores are pestilential, and often to such a degree as to lead to their entire desertion, more frequently to their abandonment in summer. And to avoid wet lands, or low lands, is not always a sufficient precaution; since the most pestilential parts of the maremma of Tuscany are dry, and since the annual mortality of Sienna from fevers, even without epidemics, is one in ten. In the north of Italy, the great plain is similarly insalubrious; though the more unhealthy district does not commence until we arrive at Mantua, extending thence to the sea. Of the Mediterranean islands, I can only afford room to say, that the same rule holds good as to the sea coasts, while the entire of Greece in the same circumstances is similarly unhealthy, and subject to autumnal fevers in as great a degree as the worst parts of Italy. The same is true of Spain and Portugal, and the same rule also will be a guide; namely, that malaria is to be expected in all the flat grounds, even when under cultivation, and at all the exits of rivers on the sea, even though no marshes should be present: and if I were desirous to name any tract of land in Spain peculiarly [p057] insalubrious, it would be the province of Valencia; while Carthagena is almost invariably fatal even to those who, as labourers, are compelled to resort to it for the needful work of its port, even during a few days. Of France, little as it has hitherto been suspected by those who, associating the term malaria with Italy, have been accustomed to consider it as peculiar to that country, it would scarcely be untrue to say that it contains as large a portion of insalubrious territory as Italy itself, and produces fever and disease of as great severity and extent, not merely on its sea coasts, but over very extensive tracts in its interior. And this insalubrity may be conjectured, when there are entire districts in which the average of life does not exceed twenty, and in which the entire people are diseased from their births to their graves. Such tracts are found chiefly on the course of the Loire, and some other of the great rivers; and among them, Bresse in the Lyonnais, the plain of Forez, and Sologne in the Orleannais, are of the most notorious; while the coasts of Normandy, and the whole of low Britanny, are similarly subject to eternal intermittents, or to epidemic seasons of autumnal fevers, amounting to absolute pestilences. And how English families have suffered in this country from the incautious choice of residences in such places, will be easily ascertained by whoever shall be at the trouble of making the necessary inquiries.