The doctor was unfailingly punctual in taking his meals. Dr. Kingsley, during the fourteen years he had acted as his agent, had always been able to make sure of finding him at home at his dinner hour, half-past two o'clock. But on Friday, November 23, 1849, to his surprise and that of his family, Dr. Parkman did not come home to dinner; and their anxiety was increased when the day passed, and there was still no sign of the doctor's return. Inquiries were made. From these it appeared that Dr. Parkman had been last seen alive between one and two o'clock on the Friday afternoon. About half-past one he had visited a grocer's shop in Bridge Street, made some purchases, and left behind him a paper bag containing a lettuce, which, he said, he would call for on his way home. Shortly before two o'clock he was seen by a workman, at a distance of forty or fifty feet from the Medical College, going in that direction. From that moment all certain trace of him was lost. His family knew that he had made an appointment for half-past one that day, but where and with whom they did not know. As a matter of fact, Professor John W. Webster had appointed that hour to receive Dr. Parkman in his lecture-room in the Medical College. John W. Webster was at this time Professor of Chemistry and Mineralogy in Harvard University, a Doctor of Medicine and a Member of the American Academy of Arts and Sciences, the London Geological Society and the St. Petersburg Mineralogical Society. He was the author of several works on geology and chemistry, a man now close on sixty years of age. His countenance was genial, his manner mild and unassuming; he was clean shaven, wore spectacles, and looked younger than his years.