And, 3. To open their case to others, and tell them all, that they may help to their preservation. 4. And especially to be willing to use the means, both physic, and satisfying counsel, which tend to cure their disease. And if there be any rooted cause in the mind that was antecedent to the melancholy, it must be carefully looked to in the cure. _Direct._ II. Take heed of worldly trouble and discontent; for this also is a common cause. Either it suddenly casteth men into melancholy, or without it of itself overturneth their reason, so far as to make them violently despatch themselves; especially, if it fall out in a mind where there is a mixture of these two causes: 1. Unmortified love to any creature. 2. And an impotent and passionate mind; their discontent doth cause such unquietness, that they will furiously go to hell for ease. Mortify therefore first your worldly lusts, and set not too much by any earthly thing: if you did not foolishly overvalue yourselves, or your credit, or your wealth or friends, there would be nothing to feed your discontent: make no greater a matter of the world than it deserveth, and you will make no such great matter of your sufferings. And, 2. Mortify your turbulent passions, and give not way to Bedlam fury to overcome your reason. Go to Christ, to beg and learn to be meek and lowly in spirit, and then your troubled minds will have rest, Matt. xi. 28, 29. Passionate women, and such other feeble-spirited persons, that are easily troubled and hardly quieted and pleased, have great cause to bend their greatest endeavours to the curing of this impotent temper of mind, and procuring from God such strengthening grace, as may restore their reason to its power. _Direct._ III. And sometimes sudden passion itself, without any longer discontent, hath caused men to make away themselves. Mortify therefore and watch over such distracting passions. _Direct._ IV. Take heed of running into the guilt of any heinous sin. For though you may feel no hurt from it at the present, when conscience is awakened, it is so disquieting a thing, that it maketh many a one hang himself. Some grievous sins are so tormenting to the conscience, that they give many no rest, till they have brought them to Judas's or Ahithophel's end. Especially take heed of sinning against conscience, and of yielding to that for fear of men, which God and conscience charge you to forbear. For the case of many a hundred as well as Spira, may tell you into what calamity this may cast you. If man be the master of your religion, you have no religion; for what is religion, but the subjection of the soul to God, especially in the matters of his worship; and if God be subjected to man, he is taken for no-god. When you worship a god that is inferior to a man, then you must subject your religion to the will of that man. Keep God and conscience at peace with you, if you love yourselves, though thereby you lose your peace with the world.