Before I engage farther, in proving that the _Venereal Disease_, when it came to be confirmed, was frequently known among us some hundreds of Years before the Siege of _Naples_: I shall endeavour to refute the Opinion of those Persons, who believe it to have had its Rise there, if any such shall remain. True indeed it is, that there have not been wanting several modern Authors, who have asserted it; but I determine to make it appear to be an Error as inconsiderately, and hastily received, as started by some Chimerical Author; who, because several Writers about that time, observing the Disease to begin in the _Pudenda_, separated it from another, with which it was before confounded, must likewise take upon him to assert its being a _new_ Distemper, and to assign a certain Time and Place for its Rise. Now one might with all the Reason in the World expect, that if the Disease had its Original there, it must have been so certainly and infallibly known, that there could have been no doubtful or uncertain Opinions about it, but that the Physicians, who resided _in_ or _near_ the Place, and those more especially, who interested themselves so far as to write of it, must have, all of them to a Man, agreed upon the Certainty of a thing, the Knowledge of the Truth of which was so easily attainable. But on the contrary, _Nicholas Leonicenus_, who was the first _Italian_ Physician, that wrote of this Disease, and who lived at the very time, when _Naples_ was besieged, is so far from acknowledging it to have had its Rise there, from the _French_ Soldiers Conversation with the _Italian_ Women, and so little did he know of its true Cause, that he does not allow it to be the Consequent of impure Embraces. About this time it was likewise, that Pope _Alexander_ the VIth engaged _Gaspar Torella_ to write of this Distemper. This Pope was in League with _Alphonsus_ King of _Naples_, against _Charles_ VIII. King of _France_, to prevent his passing thro’ _Italy_, when he went to besiege _Naples_; yet this Author is so far from allowing it to have had its Original there, that he tells us, the Astrologers were of opinion, that it proceeded from I know not what particular Constellations. Nor does _Sebastianus Aquilanus_, who lived at that time, allow it to be any other than an ancient Disease; or _Antonius Scanarolius_, who wrote in 1498, which was but 4 or 5 Years after that Siege. Nor do several other Authors, then living, say one Word about this _Neapolitan_ Story. But it seems _Ulricus de Hutten_, a _German_ Kt. no Physician, positively affirms this Disease to have had its Rise there; but how he should come to know this, who lived at such a distance from the Place, and they, who were Physicians residing as it were upon the Spot, be ignorant of it, will be as much credited, as his following inconsistent Relation, which will sufficiently prove, how little care he took to be apprised of the Truth of what he wrote. This very Author tells us, the Disease