In the reign of Ptolemy Philometor, when Agatharcides lived, the commercial enterprizes of the Egyptians had begun rather to languish; on the Arabian side of the Red Sea, they did indeed extend to Sabaea, as in the time of Euergetes; but there is evidence that on the opposite coast they did not go so low, as in the reign of the latter sovereign. Agatharcides makes no mention of Berenice; according to his account, Myos Hormos had again become the emporium, and the only trade from that part seems to have been for elephants to Ptolemais Theron. It may, indeed, be urged that Berenice was not, properly speaking, a harbour, but only an open bay, to which the ships did not come from Myos Hormos, till their cargoes were completely ready. But that Myos Hormos was the great point of communication with Coptus is evident from the account which Agatharcides gives of the caravan road between these two places. Even so late as the time of Strabo, this road was much more frequented than the road between Coptus and Berenice: of the latter he merely observes, that Philadelphus opened it with his army, established ports, and sunk Wells; whereas he particularly describes the former road, as being seven or eight days' journey, formerly performed on camels in the night, by observation of the stars, and carrying water with them. Latterly, he adds, deep wells had been sunk, and cisterns formed for holding water. Every detail of the road to Berenice is Roman, and relates to periods considerably posterior to the conquest of Egypt by the Romans--a proof that the plan of Philadelphus, of substituting Berenice for Myos Hormos, had not been regularly adopted by his successors, nor till the Romans had firmly and permanently fixed themselves in Egypt.