A.D. 1558, the city of Murcia suffered from pestilence, on account of which the bishops and principal inhabitants deserted the city. This fatal epidemic extended to all parts around Murcia and to the kingdom of Valencia. The Jesuit Fathers assumed the temporal as well as the spiritual care of the plague-striken. Many of the attendants fell victims to the disease, amongst whom was the celebrated Dr. Pedro de Cabera, son of the Viscount of the same name, together with the padre Marco Antonio Fontoba. Barcelona also at this period suffered from mortal pestilence; it commenced in January, and continued unto July, when it ceased. A.D. 1563, there was a great dearth of corn and other provisions in London; famine and disease were the result, and 20,000 persons perished in consequence. France suffered from pestilence, and Barcelona was again visited by it. Burgos--a city in which all the reverend Fathers of the Society of Jesus, who administered the rites to the dying, perished,--was nearly devastated by plague, as noticed by Franco; in fine, many European cities suffered more or less during this year from epidemic disease; among which were, Frankfort, Magdenburg, Dantzic, Hamburgh, Wismar, Lubeck, Bostack, and Dresden. A.D. 1564, an epidemic prevailed in the form of fatal quinsies and spotted fever, in various parts of Europe. Barcelona again suffered from pestilence, which broke out in the month of June, and lasted unto November following. The city of Saragossa also suffered from a cruel epidemic, from May unto December, during which period there died 10,000 persons in the city alone: it was supposed that the disease was introduced from France by means of the clothes of persons who had died there from the disease. Dr. Porcell, who was singularly successful in treating the disease, wrote a work on it, and dedicated it to Don Philip II.; it was entitled ‘Informacion y Curacion de la peste de Zaragoza, y preservacion contra peste en general, por Juan Porcell Sardo, Doctor en Medicina, Zaragoza.’ The symptoms of this malady were, intense cephalalgia, sleeplessness and delirium, vomiting of bilious matter, urgent thirst, nausea, accompanied by pain in the stomach: dissection showed nothing particular in the humors; the gall-bladder was extremely large, and distended with black viscid bile,--sometimes, however, it was found empty. There was yellowness of the skin, and a similar tinge was observed internally.