Not the least of the effects of the Black Death upon England was the domestication of the foreign pestilence on the soil. For more than three centuries bubo-plague was never long absent from one part of Britain or another. The whole country was never again swamped by a vast wave of plague as in the fourteen months of 1348-49. Nor does it appear that the succeeding plagues of the fourteenth century, the _pestis secunda_, _tertia_, _quarta_ and _quinta_ were all of the same type as the first, or otherwise comparable to it. Disastrous as many subsequent English epidemics of bubo-plague were, they appear to have been localised in the North, perhaps, or in Norfolk, or confined to the young; and, above all, the bubo-plague became, in its later period, peculiarly a disease of the poor in the towns, although it did not cease altogether in the villages and country houses until it ceased absolutely in 1666. For three hundred years plague was the grand “zymotic” disease of England--the same type of plague that came from the East in 1347-49, continuously reproduced in a succession of epidemics at one place or another, which, by diligent search, can be made to fill the annals with few gaps, and, if the records were better, could probably be made to fill most years. Britain was not peculiar among the countries of Europe in that respect, although the chronology of plagues abroad has not been worked out minutely, except for an occasional province in which some zealous archaeologist had happened to take up the subject[385].