epidemics in England in 1508, 1517 and 1528 comes from Bernard André’s annals and Polydore Virgil’s history, and from the despatches of the apostolic nuncio, the Venetian ambassador and the French ambassador. The fifth and last outbreak, in 1551, called forth two native writings, one for popular use in English in 1552, and another in Latin in 1555, both by Dr Caius, physician to Henry VIII. and Edward VI.; these are indeed better than nothing at all, but they are too much occupied with pedantry and lugubrious rhetoric to be of much service for historical purposes[505]. The information about the epidemic of 1551 is so scanty as to suggest that the sickness in that year can hardly have been so severe as in 1528; the state papers contain hardly anything relating to it, and we owe nearly all our knowledge of it to the diary of Machyn, a citizen of London, to Edward VI.’s diary, and to Dr Caius. Bills of mortality had been kept in London for two or three weeks when the epidemic was at its height, from which some totals of deaths are extant. The Fifth Sweat in 1551. It was not in London that the sweat of 1551 began, but at Shrewsbury--on the 22nd of March, according to the manuscript chronicle of that town[506], or on the 15th of April, according to Caius[507]. No record remains of its prevalence at Shrewsbury; the statement of Caius, that some 900 deaths had occurred in a single city corresponds to the facts for London, and has no more reference to Shrewsbury (where Caius never resided) than it has to Norwich (as in Blomefield’s county history). The strange influence in the air or soil advanced from Salop, as we learn from Caius, by way of Ludlow, Presteign, Westchester, Coventry and Oxford, in only one of which places is anything known of it except Caius’s remark that it proceeded “with great mortality.” The best record of its prevalence on the way from Shrewsbury to London occurs in the parish register of Loughborough, in Leicestershire. Under the date of June, 1551, the register has an entry that “the swat called New Acquaintance, alias Stoupe! Knave and know thy Master, began on the 24th of this month.” Then follow the names of 12 persons who were buried in four days, and, on the next page, under the heading of “The Sweat or New Acquaintance,” the names of 7 more, all buried in three days--making a total of 19 in six days, presumably all dead of the sweat and presumably also the whole mortality from it in Loughborough, which had far heavier mortalities from the common plague in after years[508]. The date of its arrival at Oxford, on the way to London, is not known; but a physician then resident there, Dr Ethredge, has left it on record that it attacked sixty in Oxford in one night, and next day more than a hundred in the villages around; very few died of it at Oxford, which showed that the air of that university was more salubrious than at Cambridge, where the two sons of the duchess of Suffolk died[509].