The reigns of Edward VI. and Mary, full of trouble as they were in other ways, furnish hardly a single record of plague. The sweating sickness of 1551 we hear of sufficiently; and the pestilent fevers, or influenzas, in 1557-58 are not altogether without record; but of plague down to the 5th year of Elizabeth (1563) there is very little said, and that little not free from ambiguity. Sometime in that interval, or still earlier, must have fallen the pestilence at Northampton, severe enough to require the new cemetery which cardinal Pole, in a deed of March 9, 1557, ordered to be henceforth kept enclosed[586]. Only two of the many centres of sickness in England in 1558 are said to have had the infection of the type, not of fever, but of plague,--Loughborough and Chester. In the Leicestershire town the burials were numerous enough for true plague, and the cause of mortality is so named[587]. In Chester also the sickness is called the plague, and it is added that many fled the town, although the deaths were few[588]. A State paper of February 25, 1559, speaks of the county of Cheshire as “weakened by the prevalence of plague[589].” The London Plague of 1563. The activity of the plague in London in 1563 made up for its dormancy in the years preceding. The epidemic of that summer and autumn was one of the most severe in the history of the city, the mortality in proportion to the population having been tremendous. This is the first London plague for which we have the authentic weekly deaths. How they were obtained is not stated, but it was probably by the same means that furnished the plague-bills of 1532 and 1535. John Stow must have had before him a complete set of weekly bills from the beginning of June, 1563, to the 26th of July, 1566, of which series not one is known to be extant; but the totals of the weekly deaths from plague for the whole of that period are among Stow’s manuscript memoranda in the Lambeth Library[590]. After the week ending the 31st December, 1563, the weekly deaths are few, many of the weeks of 1564, 1565 and 1566 having only one death from plague, and some of them none. The following are the weekly mortalities during the severe period of the epidemic: