The epidemic of plague, which reached its height in the year 1593, began to be felt in London in the autumn of 1592[699], and is said to have caused 2000 deaths before the end of the year. On the 7th September, soldiers from the north on their way to Southampton to embark for foreign parts had to pass round London “to avoid the infection which is much spread abroad” in the city. On the 16th September, the spoil of a great Spanish carrack at Dartmouth could be brought no farther than Greenwich, on account of the contagion in London; no one to go from London to Dartmouth to buy the goods. It was an ominous sign that the infection lasted through the winter; even in mid winter people were leaving London: “the plague is so sore that none of worth stay about these places[700].” On the 6th April, 1593, one William Cecil who had been kept in the Fleet prison by the queen’s command, writes that “the place where he lies is a congregation of the unwholesome smells of the town, and the season contagious, so many have died of the plague[701].” From a memorial of 1595, it appears that the neighbourhood of Fleet Ditch had been the most infected part of the whole city and liberties in 1593; “in the last great plague more died about there than in three parishes besides[702].” The epidemic does not appear to have reached its height until summer; on 12th June, a letter states that “the plague is very hot in London and other places of the realm, so that a great mortality is expected this summer.” On 3 July the Court “is in out places, and a great part of the household cut off [? dispensed with].” The infection is mentioned in letters down to November, after which date its public interest, at least, appears to have ceased.