By secret avenues it reaches the most opulent, and severely revenges their neglect or insensibility to the wretchedness surrounding them[265].” In an address to the Committee of Police in Manchester, he instances the following cases: A family of the name of Turner in a dark cellar behind Jackson’s Row: they have been almost constantly patients of the Infirmary for three years past on account of disorders owing to their miserable dwelling. There are other instances of the same kind in Bootle Street. In Blakely Street, under No. 4, is a range of cellars let out to lodgers, which threatens to become a nursery of disease. They consist of four rooms communicating with each other, of which the two centre rooms are completely dark; the fourth is very ill-lighted and chiefly ventilated through the others. They contain four or five beds in each, and are already extraordinarily dirty. In a nest of lodging-houses in Brook’s entry near the bottom of Longmill-gate, a very dangerous fever constantly subsists, and has subsisted for a considerable number of years. He had known nine patients confined in fevers at the same time in one of those houses and crammed into three small dirty rooms without the regular attendance of any friend or of a nurse. Four of these poor creatures died, absolutely from want of the common offices of humanity and from neglect in the administration of their medicines. Another set of lodging-houses constantly infected is known by the name of the Five Houses, in Newton Street[266]. The fever in Manchester was not always malignant typhus: sometimes it had the symptoms and low rate of mortality that suggest relapsing fever. Thus, in the winter epidemic of 1789-90, very prevalent in Manchester and Salford, out of Ferriar’s first ninety patients only two died; in some the skin had a remarkable, pungent heat, in others there were profuse watery sweats; women were commonly affected with hysterical symptoms during convalescence, which was often tedious[267]. A certain number of these cases would run into “a formed typhus,” with petechiae and all the other signs of malignity; and in some seasons, as in the distressful year 1794, typhus was the usual form. Two fatal cases in children, examined after death, had peritonitis; “in the one no marks of the disease were discernible within the cavity of the [intestinal] tube;” in the other, the patient was covered with petechiae[268]. These cases of localized inflammation in typhus he compares with Pringle’s cases of spotted fever complicated with abscess of the brain.