The country is quite extensive, and an intercourse is carried on between the whites and Indians in almost every part of it. The principal settlements are on the Wallamet River and Taulatin Plains, but there are whites at the mouth of the Columbia River, the Falls, and among the Wallawalla, Cayuse, Nez Percé, and Snake Indians. Immediately after the arrival of your agent in this country, he received the most urgent calls from several of these places, if possible to come immediately and enter into such measures as would secure both the safety of the whites and welfare of the Indians. He entered upon his business with diffidence, though with great energy and decision, and his indefatigable efforts to promote the interests of this country, with his untiring industry in the performance of his duties, entitle him to the warmest respect of the members of this infant and helpless colony, and to the confidence of the honorable department which has committed to him so important a trust. Although he has been with us but a short time in his official capacity, yet it is generally believed that the measures he has adopted to regulate the intercourse between the whites and Indians, particularly in the Cayuse, Nez Percé, and Wallawalla tribes, are wisely calculated to secure the protection of the former against the aggressions of the savages, and to secure to the latter the blessings of harmony, peace, and civilization. Some time in November last news reached us from these formidable tribes that they were laying a plot for the destruction of this colony, upon which your agent, with characteristic decision, determined to proceed at once to the scene of this conspiracy, and, if possible, not only to frustrate the present designs of the Indians, but to prevent any future attempts of the same character. This laborious journey was undertaken, and, accordingly, he set out on this perilous enterprise in the dead of winter, being accompanied by six men, and though the distance to be traveled by land and water was little less than one thousand miles, and the whole journey was one of excessive labor and much suffering, yet perseverance surmounted every difficulty, and the undertaking was brought to a most happy issue. In the fitting out and execution of such an expedition much expense must necessarily be incurred, but I am fully of the opinion the funds appropriated by your agent, for the purpose of accomplishing the object of his appointment, have been judiciously applied.