"The animal body is a heated mass, which bears the same relation to surrounding objects as any other heated mass. It receives heat when the surrounding objects are hotter, it loses heat when they are colder than itself. We know that the rapidity of cooling increases with the difference between the heated body and that of the surrounding medium--that is, the colder the surrounding medium the shorter the time required for the cooling of the heated body. How unequal, then, must be the loss of heat of a man at Palermo, where the actual temperature is nearly equal to that of the body, and in the polar regions, where the external temperature is from 70 to 90 degrees lower. "Yet notwithstanding this extremely unequal loss of heat, experience has shown that the blood of an inhabitant of the arctic circle has a temperature as high as that of the native of the South, who lives in so different a medium. This fact, when its true significance is perceived, proves that the heat given off to the surrounding medium is restored within the body with great rapidity. This compensation takes place more rapidly in winter than in summer, at the pole than at the equator. "Now in different climates the quantity of oxygen introduced into the system of respiration, as has been already shown, varies according to the temperature of the external air; the quantity of inspired oxygen increases with the loss of heat by external cooling, and the quantity of carbon or hydrogen necessary to combine with this oxygen must be increased in like ratio. It is evident that the supply of heat lost by cooling is effected by the mutual action of the elements of the food and the inspired oxygen, which combine together. To make use of a familiar, but not on that account a less just illustration, the animal body acts, in this respect, as a furnace, which we supply with fuel. It signifies nothing what intermediate forms food may assume, what changes it may undergo in the body, the last change is uniformly the conversion of carbon into carbonic acid and of its hydrogen into water; the unassimilated nitrogen of the food, along with the unburned or unoxidized carbon, is expelled in the excretions. In order to keep up in a furnace a constant temperature, we must vary the supply of fuel according to the external temperature--that is, according to the supply of oxygen. "In the animal body the food is the fuel; with a proper supply of oxygen we obtain the heat given out during its oxidation or combustion."(3) BLOOD CORPUSCLES, MUSCLES, AND GLANDS