struggle, unhampered by the material drawbacks which so often confront the would-be worker in science. He desired also that the institution should be a centre of education along the lines of its work, adding thus an indirect influence to the score of its direct achievements. In both these regards the institution has been and continues to be worthy of its founder. The Pasteur Institute is in effect a school of bacteriology, where each of the professors is at once a teacher and a brilliant investigator. The chief courses of instruction consist of two series each year of lectures and laboratory demonstrations on topics within the field of bacteriology. These courses, at which all the regular staff of the institution assist more or less, are open to physicians and other competent students regardless of nationality, and they suffice to inculcate the principles of bacteriology to a large band of seekers each year. But more important, perhaps, than this form of educational influence is the impetus given by the institute to the researches of a small, select band of investigators who have taken up bacteriology for a life work, and who come here to perfect themselves in the final niceties of the technique of a most difficult profession. Thus such men as Calmette, the discoverer of the serum treatment of serpent-poisoning, and Yersin, famous for his researches in the prevention and cure of cholera by inoculation, are "graduates" of the Pasteur Institute. Indeed, almost all the chief laborers in this field in the world to-day, including the directors of practically all the daughter institutes bearing the same name that are now scattered all over the world, have had at least a share of their training in the mother institute here in Paris. Of the work of the men who form the regular staff of the Pasteur Institute only a few words need be said here. Doctors Roux, Grancher, Metchnikoff, and Chamberland all had the privilege of sharing Pasteur's labors during the later years of the master's life, and each of them is a worthy follower of the beloved leader and at the same time a brilliant original investigator.*1* Roux is known everywhere in connection with the serum treatment of diphtheria, which he was so largely instrumental in developing. Grancher directs the anti-rabic department and allied fields. Metchnikoff, a Russian by birth and Parisian by adoption, is famous as the author of the theory that the white blood-corpuscles of the blood are the efficient agents in combating bacteria. Chamberland directs the field of practical bacteriology in its applications to hygiene, including the department in which protective serums are developed for the prevention of various diseases of domesticated animals, notably swine fever and anthrax. About one million sheep and half as many cattle are annually given immunity from anthrax by the serum here produced.