But however much the stamp of any individual personality may rest upon the institute, it is officially a department of the university, just as is the Virchow Institute. Like the latter, also, its local habitation is an antiquated building, strangely at variance, according to American ideas, with its reputation, though by no means noteworthy in this regard in the case of a German institution. It is situated in a part of the city distant from any other department of the university, and there is nothing about it exteriorly to distinguish it from other houses of the solid block in which it stands. Interiorly, it reminds one rather of a converted dwelling than a laboratory proper. Its rooms are well enough adapted to their purpose, but they give one the impression of a makeshift. The smallest American college would be ill-satisfied with such an equipment for any department of its work. Yet in these dingy quarters has been accomplished some of the best work in the new science of bacteriology that our century will have to boast. The actual equipment of the bacteriological laboratory here is not, indeed, quite as meagre as it seems at first, there being numerous rooms, scattered here and there, which in the aggregate give opportunity for work to a large number of investigators, though no single room makes an impressive appearance. There is one room, however, large enough to give audience to a considerable class, and here lectures were given by Professor Koch and continue to be given by his successors to the special students of bacteriology who come from all over the world, as well as to the university students who take the course as a part of their regular medical curriculum. In regard to this feature of its work, the Institute of Hygiene differs in no essential respect from the Pasteur Institute and other laboratories of bacteriology. The same general routine of work pertains: the patient cultivation of the minute organisms in various mediums, their careful staining by special processes, and their investigation under the microscope mark the work of the bacteriologist everywhere. Many details of the special methods of culture or treatment originated here with Professor Koch, but such matters are never kept secret in science, so one may see them practised quite as generally and as efficiently in other laboratories as in this one. Indeed, it may frankly be admitted that, aside from its historical associations with the pioneer work in bacteriology, which will always make it memorable, there is nothing about the bacteriological laboratory here to give it distinction over hundreds of similar ones elsewhere; while in point of technical equipment, as already noted, it is remarkable rather for what it lacks than for what it presents.