Diego and Ana, ending with a sentence of irremissible prison and sanbenito. Ana had broken down under this wandering life of incessant vicissitudes and anxiety; she had become the victim of epilepsy, melancholia and hypochondria, when her pitiless judges sent her to prison for life in vindication of a religion of infinite love and charity.[814] An even more pitiful illustration of the miseries endured by these unfortunates, under the implacable vigilance of the Inquisition, is afforded by the case of Isabel, wife of Francisco Palos, of Ciudad Rodrigo. In 1608, when 22 years of age, she was tried by the Valladolid tribunal. Subsequently she was tried twice, in 1621 and 1626, at Llerena, twice at Cuenca, in 1653 and 1655, and finally in 1665 at Toledo. Altogether, about eighteen years were spent in these trials; the last one, in which she was thrice tortured, continued until 1670, when she was in her eighty-fourth year and eluded her tormentors by dying in prison, to be burnt in effigy with her bones as a _difunta_.[815] Little colonies of Portuguese, like that of Beas, were frequently discovered. Simon Múñoz of Pastrana, on trial at Toledo, in 1679, gave the names of twenty-nine accomplices residing there, nearly all of whom figured in an auto particular of December 21, 1680. They had long succeeded in eluding inquisitorial vigilance, for one of them, María Enríquez, then sixty years old, testified that she had been brought thither from Lisbon by her parents, when a little child and had always lived there.[816] A similar group of Portuguese, in the little town of Berin (Orense) were tried between 1676 and 1678, by the tribunal of Santiago, and furnished to the Madrid auto of 1680 two victims relaxed as pertinacious Jews--Baltasar López Cardoso and Feliz López his cousin. There were more than twenty of them in all, and they had long been settled there; Antonio López, one of them, said, in 1677, that he was thirty-two years old and had been born in Berin.[817] [Sidenote: _DECAY OF JUDAISM_]