In North America the doctrine of nullification, newly put forth, emphasized the growing differences between the Northern and Southern States. The great debate between Hayne and Webster came about casually in the course of a discussion of the sale of public lands. The topic of nullification was dragged in by Southern speakers. Webster felt called upon to uphold the cause of the Northern States. Smarting under some of his animadversions of Southern sloth, Hayne made a two-day speech in which he inveighed against the spirit of the New Englanders. His own State, South Carolina, and her sister States in the South, he declared, would defend their sovereign rights, or "perish in the last ditch." Webster's reply to those prophetic words was the grandest oratorical effort of his life. He declared for the continued union of all the States in all their strength: "Liberty and Union, now and forever, one and inseparable." Jackson's progressive foreign policy poured oil on the troubled waters. His repeal of the shipping acts of 1818 and 1823 brought about a resumption of direct trade with the West Indies. On October 5, Jackson was able to issue a proclamation announcing the opening of permanent trade with all ports of the West Indies, Bermudas, Bahamas, the Gulf of Mexico and South America. [Sidenote: Anglo-American treaty] [Sidenote: O'Connell's State trial] [Sidenote: Anti-reform utterances] [Sidenote: Wellington unpopular] [Sidenote: Fall of Ministry] [Sidenote: Earl Grey, Prime Minister]