Assassination of Berenice, and most unfortunate war thereby kindled with Ptolemy Evergetes of Egypt, 247-244. The assistance which Seleucus obtains from his junior brother, Antiochus, governor of Asia Minor, induces Ptolemy to a truce, 243; but another war ensues between the two brothers, in which Antiochus, at first conqueror, is himself soon afterwards conquered in his turn, 243-240; and during this contest, Eumenes of Pergamus greatly increases his territory at the expense of Syria, 242.--His first campaign against Arsaces, who had formed an alliance with the Bactrian king, ended in a defeat, 238, regarded by the Parthians as the real epoch of the foundation of their kingdom. In the second campaign, 236, he himself fell into the hands of the Parthians, and remained a prisoner till the day of his death, 227. 12. His elder son Seleucus III. surnamed Ceraunus, on the point of taking the field against Attalus king of Pergamus, was removed by poison. But the dominion of the Seleucidae was reestablished in Asia Minor by his mother's fraternal nephew, Achaeus; and the crown ensured to the younger brother Antiochus, governor of Babylon. 13. The long reign of Antiochus III. surnamed the Great, is not only the most eventful in Syrian history, but likewise marks an epoch, by the relations now commencing between Syria and Rome.--To earn the title of _great_ was a task of no extreme difficulty in such a line of princes. 14. Great power of Hermias the Carian, who soon became so formidable to the young monarch, that he was obliged to rid himself of him by murder. The great stand made by the brothers, Molo and Alexander, satraps of Media and Persia, who probably had an understanding with Hermias, threatened the king with the loss of all the upper provinces: it ended in the defeat of Molo, Hermias being at last no longer able to hinder the king from marching against him in person. 15. The intrigues of Hermias excited Achaeus to rebellion in Asia Minor: but Antiochus held more important, first to execute the plan he had previously traced, of ejecting the Ptolemies from their possessions in Syria; great as the success which at first attended this expedition, it was completely traversed by the battle of Raphia.--Combining with Attalus of Pergamus, Antiochus then defeated Achaeus, who, being shut up in the citadel of Sardes, was treacherously delivered into his hands.