A Manual of Clinical DiagnosisTodd, James Campbell
Science
A Manual of Clinical Diagnosis
Todd, James Campbell
Diagnosis, Laboratory
The leukocyte count is high, but lower than in the myelogenous type.
Counts of 100,000 are about the average, but in many cases are much
lower. This high {211} count is referable almost wholly to increase of
lymphocytes. They generally exceed 90 per cent. of the total number.
In chronic cases they are chiefly of the small variety; in acute
cases, of the large form. Myelocytes are rare.
The red corpuscles show the changes usual in severe secondary anemia.
Erythroblasts are seldom abundant. Blood-plaques are decreased.
3. Pseudoleukemia (Hodgkin's disease) resembles lymphatic leukemia in
that there is marked and progressive enlargement of the lymph-nodes.
There is, however, no distinctive blood-picture. The changes in
hemoglobin and red cells resemble those of a moderate symptomatic
anemia, with rather low color-index. The leukocytes are commonly
normal in number and relative proportions.
4. Anæmia Infantum Pseudoleukæmica.--Under this name von Jaksch
described a rare disease of infancy, the proper classification of
which is uncertain. There is enlargement of liver and spleen, and
sometimes of lymph-nodes, together with the following blood-changes:
grave anemia with deformed and degenerated red cells and many
erythroblasts of both normoblastic and megaloblastic types; great
increase in number of leukocytes (20,000 to 100,000), and great
variations in size, shape, and staining of leukocytes, with many
atypical forms and a few myelocytes.
The table on the following page contrasts the distinctive
blood-changes in the more common conditions.
{212} DIFFERENTIAL DIAGNOSIS OF BLOOD DISEASES
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