A Manual of Clinical DiagnosisTodd, James Campbell
Science
A Manual of Clinical Diagnosis
Todd, James Campbell
Diagnosis, Laboratory
Under normal conditions little is to be seen except great numbers of
starch-granules, with an occasional epithelial cell, yeast-cell, or
bacterium. Starch-granules are recognized by their concentric
striations and the fact that they stain blue with iodin solutions.
[Illustration: FIG. 88.--General view of the gastric contents: _a_,
Squamous epithelial cells from esophagus and mouth; _b_, leukocytes;
_c_, cylindric epithelial cells; _d_, muscle-fibers; _e_, fat-droplets
and fat-crystals; _f_, starch-granules; _g_, chlorophyl-containing
vegetable matters; _h_, vegetable spirals; _i_, bacteria; _k_,
sarcinæ; _l_, budding (yeast) fungi (Jakob).]
Pathologically, remnants of food from previous meals, red
blood-corpuscles, pus-cells, sarcinæ, and excessive numbers of
yeast-cells and bacteria may be encountered (Fig. 88).
Remnants of food from previous meals indicate deficient gastric
motility.
Red Blood-corpuscles.--Blood is best recognized by the chemic tests
already given. The corpuscles {229} sometimes retain a fairly normal
appearance, but are generally so degenerated that only granular
pigment is left.
Pus-cells.--Pus is rarely encountered in the fluid removed after a
test-meal. Considerable numbers of pus-corpuscles have been found in
some cases of gastric cancer. Swallowed sputum must always be
considered.
Sarcinæ.--These are small spheres arranged in cuboid groups often
compared to bales of cotton. They frequently form large clumps and are
easily recognized. They stain brown with iodin solution. They signify
fermentation. Their presence is strong evidence against the existence
of gastric cancer, in which disease they rarely occur.
Yeast-cells.--As already stated, a few yeast-cells may be found under
normal conditions. The presence of considerable numbers is evidence of
fermentation. Their appearance has been described (p. 130). They stain
brown with iodin solution.
[Illustration: FIG. 89.--Boas-Oppler bacillus from case of gastric
cancer (Boston).]
Bacteria.--Numerous bacteria may be encountered, especially in the
absence of free hydrochloric acid. The _Boas-Oppler bacillus_ is the
only one of special significance. {230} It occurs in the majority of
cases of cancer, and is rarely found in other conditions. Carcinoma
probably furnishes a favorable medium for its growth.
These bacilli (Fig. 89) are large (5 to 10 µ long), non-motile, and
usually arranged end to end in chains. They stain brown with iodin
solution, which distinguishes them from _Leptothrix buccalis_ (p.
270), which is not infrequently found in stomach fluid. They also
stain by Gram's method. They are easily seen with the one-sixth
objective in unstained preparations, but are best recognized with the
one-twelfth, after drying some of the fluid upon a cover-glass,
fixing, and staining with Löffler's methylene-blue or by Gram's
method.
Public-domain text, read in full here on John Shaqi.
Reviews
Reviews
No reviews yet
Be the first to share your thoughts on this work.
Elsewhere in the archive
Join the Discussion
Join the discussion
Sign in to leave a comment or review.
Sign InorCreate an account