_Secondary_ splenitis is regarded as identical with pyæmic deposits. The deposits are well defined, always at the periphery, cuneiform in shape, the apex directed inwards. Their color is darker than the surrounding tissue, and their consistence firmer. They are either converted into a cellulo-fibrous callus, which contracts and causes a cicatrix in the surface; or “into a puriform, creamy mass; or into a sanious greenish, greenish-brown, or chocolate-colored pulp.” There are also fibrinous deposits frequently found in the parenchyma of the spleen, classed by some among the phenomena of secondary splenitis, but regarded by others as a simple exudation of fibrin, from an excess of this in the blood. These deposits appear as a circumscribed yellowish mass, with a margin of darker or lighter red congestion of increased consistence, easily recognized when handling the part, “and showing under the microscope a confused mass of granular with more or less oily matter infiltrated among the remains of the parenchyma. They very commonly undergo fatty degeneration.” =Chronic Thickening of the Capsule= of the spleen is of frequent occurrence. It seems to take place at the expense of the parenchyma of the organ, and may proceed to a very great extent. It is usually pretty uniform. Ossification of the thickened fibroid layers is rare, except in old persons. =Amyloid Degeneration of the Spleen.= The disease may be limited to the Malpighian corpuscles, constituting the so-called “sago spleen,” or it may extend and implicate the pulpy parenchyma between the corpuscles. The sago spleen is more or less enlarged; its weight and density are increased. On section, the surface appears smooth, dry, and studded with glistening sago-like bodies, varying in size. An iodine solution gives them a reddish-brown color. In the more advanced stage, where the pulp is infiltrated with the new material, the organ generally is much larger than in the sago spleen. It is hard and firm; the capsule tense and transparent. The cut surface is dry, homogeneous, translucent, bloodless, of a uniform dark, reddish-brown color. The organ can be cut like wax. The corpuscles are obscured by the surrounding pulp. Morbid Growths. _Tuberculous matter_ is commonly deposited in the spleen, only in connection with general tuberculosis. It appears in the form of gray granulations, miliary crude tubercles, or yellowish cheesy masses of various sizes. _Cysts_ have been observed in the capsule of the spleen. They are small, of conical shape, and lightish red color, containing numerous granular cells, floating in a transparent liquid. _Hydatid cysts_ may be found in the spleen alone, or at the same time with one in the liver. _Cancer_ is rare. The encephaloid is the only form met with, and generally only with similar disease in the liver, stomach or omentum. Section VI. OF THE LIVER.