A practical guide for making post-mortem examinations : $b and for the study of morbid anatomy, with directions for embalming the dead, and for the preservation of specimens of morbid anatomyThomas, A. R. (Amos Russell)
Science
A practical guide for making post-mortem examinations : $b and for the study of morbid anatomy, with directions for embalming the dead, and for the preservation of specimens of morbid anatomy
Thomas, A. R. (Amos Russell)
Anatomy, Pathological; Autopsy -- Handbooks, manuals, etc.
=Congestion.= This, and its consequences, are the main features of
hyperæmia of the kidneys, which is of frequent occurrence. This
condition is almost always the result of some prior general affection,
such as the scarlatinal poison, the suppression of perspiration, or
obstructive diseases of the heart.
In a simple congestion, with perfect integrity of the renal tissue, we
find the kidney enlarged, and its weight often doubled; of a dark, red
color, and dripping with blood when cut into. The cortical substance is
somewhat softened, of a dark, red color, presenting in many cases small
dark, red spots, the result of hæmorrhagic effusion into and between the
tubercles. The Malpighian tufts are distinctly visible on the cut
surface, as minute, reddish, semi-transparent grains. In the medullary
cones, the congested vessels form long dark red streaks. If the
congestions have occurred in an otherwise healthy kidney, the capsule
can be readily peeled off.
A microscopic examination shows the Malpighian and other capillaries
loaded with blood, extravasation sometimes taking place into the capsule
of the latter, and often into the channel of the fibres.
In extreme cases of hyperæmia and congestion, a fibrinous exudation
takes place, which will be found coagulated in the tubes, forming casts
of their interior, and consisting of a granular or homogeneous material,
entangling blood-globules, and often some particles of detached
epithelium.
=Hæmorrhage.= As a result of acute congestion, or from injury from
falls, blows, or wounds of the kidneys, blood may be effused, either
beneath its capsule, or within the sinus, constituting hæmorrhage of the
kidney.
=Nephritis.= This differs in no material respect from common
inflammation of other parts, and like it, often passes into suppuration.
Its most common causes are:—Excess in the use of irritating and
alcoholic drinks; abuse of diuretics; blows or falls on the loins; the
presence of renal calculi; and, according to some authors, a peculiar
morbid state of the blood, such as gives rise to carbuncles.
This disease can be distinguished from the inflammatory form of Bright’s
Disease, during life, by its generally affecting only one kidney, by the
much greater pain and tenderness in the lumbar region, by the retracting
of the testicles, and the higher degrees of febrile excitement. Then,
too, the deeply-colored urine which is voided, contains little or no
albumen.
In a case of nephritis, unattended with the formation of pus, a
_post-mortem_ would probably fail to distinguish it from the condition
of congestion just considered. Where suppuration was about taking place,
the microscope shows the cortical tubes so distended and crowded
together by infarcted epithelium, as to be scarcely distinguishable; in
some parts the basement membrane gone, and their contents a uniform mass
of nuclei and granular matter. The medullary tubes are also infarcted
and opaque.
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