On the 3d of April, I returned from Boston, and almost immediately went to work with some of our lady-managers to order beds and to furnish the house and dispensary, and also to superintend the internal changes. After five weeks of hard work, I had the pleasure, on the 15th of May, 1857, of listening in the wards of the New-York Infirmary to the opening speeches delivered by the Rev. Henry Ward Beecher, Dr. Elder, and Rev. Dudley Tyng. A few days afterwards, I admitted the first house-patient and opened the dispensary, which I attended two days in the week; Drs. Elizabeth and Emily Blackwell taking charge of it for the remaining four days. I had offered two years' gratuitous services as my contribution to the Infirmary, remaining there not only as resident physician, but also as superintendent of the household and general manager; and attending to my private practice during the afternoon. The institution grew rapidly, and the number of dispensary patients increased to such an extent, that the time from seven in the morning until one in the afternoon was wholly occupied in the examination of cases. In the second year of the existence of the Infirmary the state of Dr. Elizabeth Blackwell's health compelled her to go to Europe: and for nine months Dr. Emily Blackwell and I took charge of the business, which at this time was considerable; the attendance at the dispensary averaging sixty daily. During the course of this year, I received letters from some of the Trustees of the New-England Female Medical College in Boston, inquiring whether I were inclined to take charge of a hospital in connection with that institution. A consultation on the subject with Drs. Elizabeth and Emily Blackwell seemed to prove to us, that by doing this, and helping the college to attain its objects, we could probably best aid the cause of the medical education of women. After hesitating for a long time what course to pursue, I went to Boston in the spring of 1859, in order to define in a public address my views and position in respect to the study of medicine. I found so great a desire prevailing for the elevation of the institution to the standard of the male medical colleges, and such enthusiasm in respect to the proposed hospital, that I concluded at once to leave the Infirmary; Dr. Elizabeth Blackwell's absence having proved that it could be sustained by two, not only without loss, but with a steady increase, secured by the good done by its existence. Having fulfilled my promise of two years to the institution, on the 5th of June, 1859, I left for Boston, where I am now striving to make the hospital-department as useful as the New-York Infirmary is to the public and the students.