The persecutions of Mary's reign, if they had not made England Protestant, had at least made it bitterly anti-Roman Catholic; and this, at a time when the King of Spain was the recognised protector of the Pope, meant anti-Spanish. This served to remove any disinclination to attack our old ally. At the same time, Englishmen began to be much more effectively desirous of sharing in the wealth to be obtained by trade with the New World They were impatient at the thought that they were to be for ever shut out from the commerce of the East and the West Indies by a decision of a Pope of the previous century, who had given the Spaniards everything to the west of the famous line drawn from north to south, a hundred leagues to the west of the Azores, and had left the Portuguese the exclusive right to everything in the East. We did not recognise the Pope's right to dispose of what did not belong to him, and were minded to have our share of the good things lying beyond the line. The Spaniards would hear of no such pretension, and, though they were ready enough to trade with us in Europe, insisted upon treating all seamen of other nations whom they found in America as pirates. According even to the principles of some of their own thinkers, this refusal to trade was a fair justification for a war. Elizabeth was, however, by no means prepared for open hostilities with Spain. All she would do was to refuse to recognise the right of the Spaniards to exclude her subjects from trading with the Indians. Therefore they were free in her opinion to go to the New World, and if the Spaniards refused to recognise their trade as legitimate, Elizabeth for her part was not inclined to forbid her subjects to defend themselves against what she considered unfair interference. The causes of dispute between the queen and King Philip, apart from this, were many and various. Thus it got to be known among enterprising Englishmen that if they could make their hand keep their head from the blow of the Spaniard, they had nothing to fear from the queen when they came home from poaching expeditions on his preserves. For men who had, or who only affected to have, religious motives, and who had the most genuine desire to gain riches, this hint was enough, and so the third year of the queen's reign saw the first voyage of Hawkins to the West Indies.