1842 334 350 ———— ————— Mean 377, or about one inhabitant daily dies of small-pox in Glasgow. A confident opinion is expressed that the decrease of small-pox in the metropolis is ascribable to the extension of vaccination. The rate of reduced mortality from that disease has continued during the present year; and the average of the present rate, as compared with the average preceding the extension of vaccination, would give a reduction of 946 deaths and funerals from 1652 annually. But as not one attack in ten of small-pox usually proves fatal, the reduction of the number of deaths may be taken as representing a reduction of some 9,460 cases of sickness. The amount paid from the poor-rates for vaccination in the metropolis was 1701_l._, which at the average fee gives 22,680 of the worst conditioned and most susceptible cases out of about 56,000, in which vaccination was successfully performed. The attention directed to the subject has also promoted the extension of vaccination, by others than the appointed vaccinators. The various expenses of each case of sickness to the sufferers, inclusive of medicines, may perhaps, on a low estimate, be represented at 1_l._ each case; and taking half the average expenses of funerals for the 946 funerals saved, the total expense of funerals and of sickness saved by the expenditure of the sum stated of 1701_l._ in well-directed measures of prevention, would exceed 16,000_l._ in the metropolis alone. Throughout the whole country, the deaths from small-pox in 1840 were 10,434, as compared with 16,268 in 1838, on which, if the reduction may be ascribed to the extension of vaccination solely, pounds of immediate expenses must have been saved by the expenditure of half crowns,—in other words, upwards of 90,000_l._ in money has been saved by the expenditure of about 12,000_l._ in vaccination.