[Footnote 188: _La Goutte et le Rheumatisme_, Paris, 1857.] [Footnote 189: Reynolds's _Syst. Med._, 1870, p. 951.] [Footnote 190: _St. George's Hospital Reports_, vol. vi. p. 111 _et seq._] Greenhow[191] has treated 43 cases with iodide of potassium and quinine, and says that his experience of this method contrasts favorably with that of salicine and salicylate of soda. However, pneumonia supervened in 3 cases while under treatment; cardiac inflammation arose in 6 cases (= 14 per cent.) after admission; single relapses of short duration occurred in 21 per cent.; and, excluding two cases in which the treatment was soon discontinued and 7 very mild cases, the remaining 34 cases were on the average each thirty-six days in hospital. Under this method relapses were less frequent (21 per cent. instead of 26 per cent.), and stay in hospital longer (36 instead of 30.4 days), than under that by the salicylates; but the number of cases treated is too small to base a final opinion upon. He prescribed 5 grains each of iodide of potassium and carbonate of ammonia three or four times a day, and 2 grains of quinia with three of extract of hyoscyamus in pill as often. This method, in principle at least, resembles that recommended by DaCosta, who administers in uncomplicated cases bromide of ammonium in 15- to 20-grain doses every three hours, and as soon as the acute symptoms have disappeared follows it by quinia in fair doses. It has not come into general use in this country, although its eminent proposer published his cases in 1869.[192] [Footnote 191: _The Lancet_, i., 1882, 913.] [Footnote 192: _Pennsylvania Hospital Reports_, vol. ii., 1869; _New York Medical Record_, September, 1874, p. 481.]