A system of practical medicine. By American authors. Vol. 4 : $b Diseases of the genito-urinary and cutaneous systems. Medical ophthalmology, and otology
Science
A system of practical medicine. By American authors. Vol. 4 : $b Diseases of the genito-urinary and cutaneous systems. Medical ophthalmology, and otology
Medicine -- Practice
Sarcoma, primitive or secondary, of the kidney is a somewhat rare
occurrence, but most frequent in children. The whole kidney may be
transformed into a mass occupying its place and somewhat resembling it
in form, but many times exceeding it in bulk and weight. Such a tumor
may largely distend the abdominal cavity and compress its contents.
Upon section we often find a substance varying greatly in consistence,
from almost fibrous hardness to cavities filled with grumous material
broken down by fatty degeneration and often colored by hemorrhage. In
the interior may be found remains of the pyramids and cortical
substance occupying their usual relative positions, but as it were
distended, these portions being surrounded by a much thicker layer of
purely abnormal neoplasm, probably connected with the capsule and its
surrounding fat. In other cases all traces of normal form and structure
may have disappeared. The microscopic structure of such a growth
presents no peculiarity except so far as the arrangement of cells in
the normal gland may be followed to a certain extent in the
less-altered portions of the tumor. Besides this total destruction of
the kidney, it is not uncommon to find nodules involving a part of one
or both the organs, and more or less distinctly marked off from the
healthy portion.
The origin of sarcomata involving the kidneys may be the subperitoneal
cellular tissue or the neighboring organs. As a primary disease sarcoma
of the kidneys is very rare.
True cancer or carcinoma of the kidney is not a common disease, and is
said to have been found 12 times in 447 cases of cancer of various
organs. It may be primary or secondary, and a description of the gross
appearances would be essentially the same as that of the sarcoma. The
tumor does not, however, usually attain so large a size, and the amount
of degeneration of neighboring organs and of ulceration is greater.
Calculi are often found in cancerous kidneys.
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