A system of practical medicine. By American authors. Vol. 4 : $b Diseases of the genito-urinary and cutaneous systems. Medical ophthalmology, and otology
Science
A system of practical medicine. By American authors. Vol. 4 : $b Diseases of the genito-urinary and cutaneous systems. Medical ophthalmology, and otology
Medicine -- Practice
LESIONS.--If the congestion has not existed for a long time, we find
the kidneys increased in size and their weight great in proportion to
their size. They are of an unnatural hardness--a hardness which can be
imitated by injecting the blood-vessels of a normal kidney with water.
The capsules are not adherent, the surfaces of the kidneys are smooth.
Both the cortical and pyramidal portions are congested, and this
congestion gives the entire organs a peculiar reddish, livid color. No
lesions are found in the Malpighian bodies, tubes, stroma, or
blood-vessels, except that the epithelium of the convoluted tubes may
be a little swollen.
If the congestion has lasted for a longer time, the kidneys may
continue to be large or they may be somewhat reduced in size; the
weight remains out of proportion to the size. There are the same
unnatural color and consistence. The capsules are now often slightly
adherent and the surfaces of the kidneys finely nodular. In the cortex
there may be patches of new connective tissue enclosing atrophied
tubules, or there may be a more diffuse growth of connective tissue
separating the tubes from each other. In the convoluted tubules the
epithelial cells may be swollen and finely granular, or very much
swollen and coarsely granular, so as to nearly fill the tubes, or
flattened so that the cavities of the tubes are {70} unnaturally large.
The tubes may also contain cast-matter and detached and broken
epithelial cells. The capsules of the Malpighian bodies may be a little
thickened and the capsular endothelium swollen. In the pyramids the
epithelium of the straight tubes may be granular and detached, and
there is often cast-matter in the looped tubes. It is difficult to tell
whether there is any real change in the veins of the kidney.
As a result of the same interference with the venous circulation,
similar changes are found in other parts of the body--in the lungs,
liver, spleen, stomach, small intestine, and pia mater. In all these
organs there is, first, simply a venous congestion, then after a time
structural changes are added. Formation of new connective tissue and of
new functional cells of the particular organ, degeneration of these
cells, dilatation and tortuousness of the small veins and capillaries,
are regularly present. The kidney lesion, therefore, is only one of a
number of lesions, all dependent on a common mechanical cause.
SYMPTOMS.--Of the persons who die with chronic congestion of the
kidney, a large number present marked symptoms during life, but it is
difficult to determine how largely these symptoms are due to the
congestion of the kidney.
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