642. Whenever the cuticle is exposed to moderate and repeated friction, it becomes thicker and tougher, as may be seen in the cuticle of the lady's finger that plies the needle and in the hard or callous appearance of the hands of farmers masons, and other mechanics. This enables them to handle the utensils and materials used in their vocations without pain or inconvenience. _Observations._ 1st. When the joints of the feet are subjected to moderate and continued pressure or friction, frequently one or more of the papillæ enlarge. This is accompanied with a thickening of the layers of the cuticle, which is termed a "callosity," or "corn." These thickened layers of the cuticle are broad at the top and narrow at the bottom, and the enlarged mass is conical, with the point innermost. When pressed upon by a tight shoe, these sensitive papillæ cause pain. -=-=-=-=-=-=-=-=-=-=-=-= How is the thickness of the cuticle mainly formed? 641. Describe the changes of this membrane. Show the necessity of this constant growth. 642. How does moderate and repeated friction affect the cuticle? Give examples. What is the benefit derived from having the cuticle thus changed? What is the result if the joints of the feet are subjected to moderate and continued pressure? What is the form of a "corn"? -=-=-=-=-=-=-=-=-=-=-=-= 2d. To remove these painful excrescences, take a thick piece of soft leather, somewhat larger than the corn; in the centre punch a hole of the size of the summit of the corn, spread the leather with adhesive plaster, and apply it around the corn. The hole in the leather may be filled with a paste made of soda and soap, on going to bed. In the morning, remove it, and wash with warm water. Repeat this for several successive nights, and the corn will be removed. The only precaution is, not to repeat the application so as to cause pain. 643. Let a person unaccustomed to manual labor, trundle the hand-cart, or row a boat, for several successive hours, and the cuticle upon the palms of the hands, instead of becoming thicker by use, is frequently separated from the subjacent tissues, by an effusion of serum, (water,) thrown out by the vessels of the true skin. Had the friction been moderate, and applied at regular intervals, instead of blisters being formed upon the inside of the hands, material would have been thrown out to form new layers upon the lower surface of the cuticle.