_Head._ Dura mater vascular; some spots of ecchymosis between its laminæ; arachnoid vascular, with effusion of viscid serum between it and pia mater. Between the arachnoid and the pia mater covering the superior part of the right hemisphere a layer of coagulable lymph of a yellow colour, on the removal of which the pia mater beneath it appeared entire. Shreds of coagulable lymph were also found at the base of the brain where there was more serum than natural as well as in the ventricles. Substance of the brain highly vascular. Viscera of thorax and abdomen healthy. CASE XXIX. ISAAC COOMBES, æt. 60, weaver. Admitted on 9th day of fever: at present no pain of head; some sleep; face pallid; great prostration; no thoracic or abdominal symptoms. 15th. Convalescent. 21st. Attacked suddenly with shivering, heat, vomiting; no pain of head or of any organ; pulse 96. 22d. Continues quite free from pain, but no sleep; extreme restlessness; great prostration; skin warm and dry; pulse 84. Died following morning. _Head._ Between the pia mater and the arachnoid a large quantity of coagulable lymph of a yellow colour, with which indeed the arachnoid appeared to be universally lined, and which in some places was very thick. Substance of the brain highly vascular, being exceedingly full of bloody points, and in some places stained; three or four ounces of serum in the ventricles, at the bottom of each of which lay about a drachm of pus. The spinal sheath contained the same kind of substance, while the cord itself presented a healthy appearance. _Thorax._ Right lung gorged with blood and partly hepatized. _Abdomen._ Spleen soft; other viscera healthy. CASE XXX. SUSANAH STAMMERS, æt. 9, destitute. Admitted on the 8th day of fever. Attack commenced with severe pain of the head which continues with almost equal violence; little or no sleep; eyes dull and heavy; face flushed; pulse 126; slight uneasiness of chest on full inspiration; no cough; no tenderness of abdomen; tongue loaded with white fur; red at point; bowels purged. 9th. Pain of head quite gone; less sensible; countenance more dull and heavy; pulse 120; abdomen tender. 11th. Delirium, with much talkativeness; pulse 112. 14th. Coma; bowels continue purged. 15th. Abdomen tender, swollen, rounded at navel. 19th. More sensible; more tranquil sleep; delirium gone; pulse 110. 27th. No coma nor delirium; tranquil sleep; tongue moist, cleaning; pulse 108 feeble. 45th. Appeared upon the whole to be convalescing, but in an exceedingly slow and imperfect manner; there was a remarkable vacancy in her countenance, almost amounting to a fatuous expression; and her mind was peevish and childish. On this day she was seized suddenly with convulsions of extreme violence, and died within twenty-four hours after the attack.