11th. Less sensible: drowsy; delirium; three stools. 12th. Insensibility increased; drowsiness approaching to coma; cheeks dusky; tongue with dark brown crust, dry; stools in bed; pulse 102, weak. 16th. Abdomen tender; tongue not to be protruded; three stools all in bed; pulse 130, extremely weak; great prostration. 17th. Countenance sunk; respiration short and hurried; four stools; more prostrate. 18th. No change excepting that the prostration is still greater. Died. _Abdomen._ Mucous membrane of ilium and cæcum extremely vascular, and contained several small ulcers, some of which were merely the abraded points of enlarged mucous glands; other glands in the neighbourhood much enlarged but not ulcerated; mesenteric glands very much enlarged; liver mottled; spleen larger than natural; pancreas indurated. _Head._ Arachnoid highly vascular; substance of brain natural; gelatinous effusion between the arachnoid and pia mater; half an ounce of serum at base. _Thorax._ Viscera healthy. CASE LXV. JAMES GANNICOTT, æt. 8. Duration and progress of disease unknown; abdomen tender; lips and tongue sordid; bowels purged; comatose; pupils dilated, but sensible to light; expression of eyes dull and vacant; pulse 125. 2d day after admission. Abdomen no longer tender; three stools; insensibility continues; frequent screaming; pulse 116. 3d. Perfectly insensible; all nourishment refused; stools and urine in bed; pulse 120. Died next morning. _Abdomen._ Peritoneal coat of ilium vascular; its mucous coat contained numerous ulcers which varied much in size; but all of them were raised above the surface and defined and regular in their margins; mucous glands throughout the entire intestine diseased, and many of them in different stages of disease; some were only enlarged; others enlarged and inflamed; others ulcerated at the apex; others ulcerated throughout; so that the largest ulcers appeared to be diseased glands in the last stage of ulceration; mesenteric glands prodigiously enlarged and hung over the abdominal vessels like a bunch of grapes of the largest size; rest of the intestines healthy excepting that they were much contracted and intussuscepted in several parts. _Head._ Dura mater adherent with preternatural firmness to the skull; vascular; pia mater highly vascular; substance of brain vascular and firm; slight effusion between the membranes. _Thorax._ [Pluræ of right side adherent;] substance of both lungs healthy. CASE LXVI. HENRY TODD, æt. 18. Duration and progress of disease unknown; abdomen tender on pressure; tongue coated with dirty yellow crust, red at tip; perfectly insensible; delirium; eyes, glistening; pulse 120, feeble. 2d day after admission. Little change excepting that the coma is more deep; abdomen less tender; two stools; pulse 124. 3d. Coma undiminished; respiration short, hurried, rattling; stools in bed; pulse 132; great prostration. 4th. Died.