_Abdomen._ Mucous membrane of greater part of small intestines much inflamed; that in lower part of ilium quite black and nearly sphacelated, containing several spreading ulcers; colon throughout of darker colour than natural; mucous membrane of rectum highly vascular; spleen enlarged and softened; [bladder thickened and vascular.] _Head._ Arachnoid opake and milky, covering a large quantity of gelatinous fluid. _Thorax._ [Pleuræ of left side generally adherent, of right less extensively adherent;] substance of both lungs healthy. CASE LXXVIII. MARGARET PENNIFOLD, æt. 20, servant. Admitted on the 8th day of fever, which, besides the ordinary symptoms, commenced with pain and tenderness of bowels: at present, abdomen tender, especially the epigastrium; tongue very red, sore, and cracked; lips and teeth sordid; much thirst; some uneasiness of chest on full inspiration; slight cough; some pain of head, especially in occiput; scarcely any sleep; mind much confused during the night, scarcely distinct during the day; pulse 105. 9th. No pain; tongue the same; three stools; slept some; mind more distinct; pulse 100. 11th. No pain; some cough; face flushed; colour of cheek dusky; voice hoarse. 12th. Little change; pulse 108. 15th. Still says she is free from pain; no tenderness of abdomen on firm pressure; tongue very red and dry; four stools, mixed with a large proportion of blood; rather more cough; sleeps well; pulse 116. 16th. Stools mixed with blood; pulse 117. 17th. Three stools, dark and offensive but without blood; pulse 100; other symptoms the same. 19th. Stools in bed; much prostration; pulse 120, very weak; respiration difficult. 20th. Vomiting; pulse 120, weaker. 21st. Vomiting continues; six stools; mind confused: pulse 120. 22d. Vomiting has ceased; deglutition difficult; face collapsed and cadaverous; five stools in bed; great prostration; pulse 117, extremely weak. Died in the night.