JOHN M’CARTY, æt. 22, labourer. Admitted on the 22d day of fever; complaint commenced with symptoms of severe cold; at present, slight pain of chest; cough, inducing pain in the abdomen, which is not tender; pain of head gone; eyes injected and suffused; face flushed; tongue brown and dry; bowels stated to be regular; pulse 99, weak. 23d. Cough very severe; abdomen not tender; tongue dry, brown and cracked; four stools; no pain of head; face flushed; eyes ferrety; pulse 90. 24th. Mind more confused; eyes more injected; delirium. 25th. Insensibility increasing; no sleep; tongue more dry and brown; lips and teeth sordid; four stools; pulse 96. 26th. Constant delirium; stools and urine in bed; pulse 104. 28th. Died. _Head._ Membranes and substance of brain vascular; more fluid than natural in ventricles. _Thorax._ Mucous membrane of bronchi vascular; [pleuræ of right side slightly adherent.] _Abdomen._ Mucous membrane of jejunum, cæcum and ilium very much ulcerated; spleen soft; other viscera healthy. CASE CIV. SARAH NASH, æt. 14. Admitted on the 22d day of disease; pain of head appears to have been very severe but it has now wholly subsided; lies quite insensible; pupils dilated, but contractile; muscles of extremities quite rigid; hands clenched; arms and legs extended and inflexible; no tenderness of abdomen on fullest pressure; tongue brown and dry; no stool for four days; pulse 110, extremely feeble and indistinct. 23d. Muscles of lower extremities rather less rigid; hands continue clenched; eyes in general closed; when opened appear injected and suffused; much grinding of the teeth; great restlessness; noisy delirium; two stools; pulse 126, stronger. 24th. Great restlessness; scarcely any sleep; almost constant grinding of the teeth; pulse 129, of good power. 26th. So restless that the pulse cannot be counted; exceedingly peevish; began to take two grains of calomel with half a grain of opium every four hours. 27th. Little change excepting that she is now sensible of some pain in the epigastrium on full pressure, and acknowledges some pain in the head; pulse 142. 32d. No amendment in the cerebral symptoms, and the strength is diminished; the mercurial odour is already quite evident, and the mouth is slightly ulcerated; no ptyalism; pulse 126, weak; calomel and opium omitted. 36th. Noise and delirium continue; ulceration of mouth gone; pulse 140, very weak. Calomel and opium were again resumed. 27th. Slight ptyalism; no improvement; pulse 130, extremely weak and indistinct. 38th. Ptyalism continues; sinking. Died. _Head._ Membranes vascular; substance of brain much softened; effusion between all the membranes and into the ventricles. _Thorax._ Bronchi of both lungs vascular, and contained a large quantity of purulent matter; right lung much hepatized; left slightly consolidated. _Abdomen._ Ilium and cæcum very much ulcerated; spleen very firm, contained one tubercle; other viscera healthy.