9th. Pain of limbs gone; tongue nearly clean; two stools; pulse 84. 10th. Convalescent. 13th. Dismissed cured. CASE II. GEORGE WALKER, aged 17. Admitted May 5th, 1828. Six days ago seized with shivering, succeeded by heat, loss of strength, and pain of head. At present complains especially of head-ache; ardent thirst; no pain of chest; no cough; no pain of abdomen, back, or extremities; skin cool; face natural; tongue, except at the point, covered with a thick dirty fur; much thirst; no appetite; sleeps badly; bowels costive, having had no stool for the last three days; pulse 98, of good strength. 7th. Heat of skin nearly natural; pain of head almost gone; no pain of limbs; tongue still much loaded; some thirst; three stools; pulse 72; slept much better. 8th. Tongue much less loaded; less thirst; five stools; pulse 60. 11th. Convalescent. 14th. Return of head-ache, and, on the day following, the tongue again became white; but these symptoms disappeared the succeeding day, and, on the 27th, he was dismissed cured. These two cases afford fair specimens of the combination of symptoms, and of the degree of their severity, in the synochus of London, as it occurs in its mildest form. CASE III. EMMA GLADISH. Admitted into the hospital on the 12th day of fever. Attack commenced with usual symptoms. The pain in the head, which had been severe for some time, had entirely subsided on the day of her admission. The mind was now quite indistinct; she could scarcely answer any question that was put to her; the eyes were dull and heavy; she had no sleep; there was great restlessness, and occasionally wandering delirium; there was no tenderness of abdomen; the tongue was red, furred and dry; the stools were passed in bed; the pulse 105, of good power. 13th. Sleep rather more tranquil; less wandering; mind a little more distinct; stools still passed in bed; pulse 100. 14th. Much noise through the night; occasionally started out of disturbed sleep with screaming; tongue red, glazed and dry; stools passed in bed; pulse 96. 15th. Rather more sleep; talkative delirium; tongue somewhat cleaner; pulse 100. 16th. Longer and more tranquil sleep; mind more distinct; expression of eyes still dull and heavy; tongue more clean, more moist; stools only partly passed in bed. 17th. More sleep than on the preceding night; mind still more distinct; complains to-day of some tenderness of abdomen on pressure; tongue nearly clean; two stools no longer passed in bed; pulse fallen to 72. 19th. Slept well; mind clearer; eyes more animated; expression of countenance brighter; other symptoms the same. 26th. Continues to improve; skin cool, soft, and moist; pulse 78.