Hence irritation of the mucous membrane which lines the genito urinary passages may alone cause venereal excitement, and consequently onanism, independent of any affection of the nervous centres. This fact is highly essential on account of the important indications which may be deduced from it. Aware of the possibility of its existence, the physician will be more attentive to discover this irritation; he will find it more frequently and may in a degree prevent a fatal habit: he will also carefully remove every cause of irritation from the mucous integument of the genital parts and discuss as promptly as possible the inflammations which may be developed there. The mode of doing this is by attending to the following rules. To keep the sexual parts perfectly clean by repeated ablutions: to forbid all excesses of the table, and the use of such food and drinks as tend to render the urine more irritating, and the genito urinary mucous surface more irritable; hence to discard the use of wine, liquors, coffee, tea, spices, beer, particularly that made strong with hops: to allay irritations of the interior of the rectum, around the anus or those affecting the integuments around the genital organs. When children complain of itching around the anus, you must ascertain whether this be not caused by ascarides which is easily done by inspecting the parts and the feces: no means should be spared to get rid of these worms when they exist:[1] and finally the most efficient remedies should be used to cure the itching of the genitals as soon as this affection commences. Ozanam communicated to the academy of medicine August 12, 1828, a very acute case of nymphomania which had resisted antispasmodics, narcotics, cold baths, &c.; and which was finally cured by applying to the internal labia and clitoris a solution of four grains of nitrate of silver in an ounce of water. There was a marked inflammation of the parts to which this was applied. (_Rev. Med._, _Sept. 1828._) In 1833, we employed successfully another remedy, for a lady thirty-four years old and subject to nervous affections. She experienced a feeling of heat and irritation in the vulva and vagina which caused her excessive trouble. Solutions and injections of an infusion of the wild cherry-tree, produced no relief. The introduction into the vagina of a pledget of lint moistened with a solution of the extract of belladonna, (one grain to the ounce,) had a better effect. Different symptoms indicated the absorption of this drug into the system and the irritation disappeared. But it returned a few days after, and we then advised the application of ice within the vagina which relieved her, and finally brought about a permanent cure.