In the preceding case we can remark, in addition to the symptoms of the cerebral affection, the symptoms of the exhaustion of the cachexy, presented by individuals who have been reduced very low by onanism. A similar state is seen in the following case related by Tissot. Here the encephalic affection, to judge of it by the throwing back of the neck, and the violent pains experienced by the patient in this part, seemed to be situated in the cerebellum, medulla oblongata, or in those parts of the arachnoid membrane which are near them. L. D---- was by profession a watchmaker. He had lived prudently, and had enjoyed a good state of health, till he was about seventeen years of age. At this period, he gave himself up to masturbation, which he repeated every day, sometimes even to the third time; and the ejaculation was always preceded and followed by a slight insensibility, and a convulsive motion in the extending muscles of the head, which drew it very much back, whilst the neck was extremely swelled. A year had not elapsed, before he began to feel a great weakness after every act. This notification was not sufficient to rescue him from his filthy practices: his soul, already devoted to this base habit, was incapable of forming any other idea, and the repetition of his crime became every day more frequent, till such time as he was in a state which gave reason to apprehend his death. Too late grown wise, the evil had already made so great a progress, that he was incurable; and the genital parts were become so easily irritated, and were so weak, that it was no longer necessary that this unhappy youth should be an agent, in order to shed his seed. The slightest irritation immediately procured an imperfect erection, which was constantly followed by an evacuation of this liquor, which daily increased his weakness. This spasm, of which he was not before sensible but in consummating the act, and which ceased therewith, was now become habitual, and frequently attacked him without any apparent cause, and in so violent a manner, that during the whole period of the fit, which sometimes lasted fifteen hours, and never less than eight, he felt such violent pains in the back part of the neck, that he did not scream out, but absolutely howled; and all this while it was impossible for him to swallow either solids or fluids. His voice was become hoarse; but I did not observe that it was more so while the fit continued. He entirely lost his strength, and was obliged to give up his profession, being altogether incapacitated: thus overwhelmed with misery, he languished, almost without any assistance, for some months; and was the more to be pitied, as what memory he had remaining, and which he was at length entirely bereft of, only served him to take an incessant retrospect of the cause of his misfortunes, which were increased by all the aggravating horrors of remorse. I heard of his situation, and went to him; I found