a being that less resembled a living creature than a corpse, lying upon straw, meager, pale, and filthy, casting forth an infectious stench; almost incapable of motion, a watery palish blood issued from his nose; saliva constantly flowed from his mouth: having a diarrhœa, he voided his excrement in the bed without knowing it: he had a continual flux of semen; his sore, watery eyes were deadened to that degree, that he could not move them: his pulse was very small, quick, and frequent: it was with great difficulty he breathed, reduced almost to a skeleton in every part, except his feet, which became œdematous. The disorder of his mind was equal to that of his body; devoid of ideas and memory, incapable of connecting two sentences, without reflection, without being afflicted at his fate, without any other sensation than pain, which returned with every fit, at least every third day. Far below the brute creation, he was a spectacle, the horrible sight of which cannot be conceived, and it was difficult to discover that he had formerly made part of the human species. I had immediate recourse to the assistance of strengthening remedies, in order to remove these violent spasmodic fits, which so dreadfully brought him back to sensibility only by pain: I contented myself with having given him some ease in this respect, and I discontinued administering remedies, which could not ameliorate his condition; he died at the end of a few weeks, in June, 1757, his whole body having become dropsical. In a case related by Bouteille, surgeon-general of the hospital at Lyons, most of the symptoms resulting from the cerebral affection existed in the right side of the body, and consequently indicated an affection of the opposite side of the cerebrum. The patient was a young girl twelve years old, whose constitution was weak and irritable, and very slightly developed--doubtless, on account of the enervating habit of onanism, in which she had indulged for several years, and which her mother’s vigilance could not prevent. Just after recovering from a severe illness, which yielded readily to remedies, this young girl was very much terrified, which had a great deal of influence upon her, as she was extremely sensitive; her sensibility being increased by the weak state of her nervous system, produced by onanism. Soon after, she was affected by slight convulsive motions in the right foot and arm, accompanied by a disagreeable pain in the right knee and in the sole of the foot of the same side. Notwithstanding the use of remedies, the disease increased, and she was soon unable to carry her food to her mouth, her arm was so much agitated. The appetite was variable, and the pulse was regular. Sometimes, and contrary to her usual custom, the patient was silent; sometimes she was extremely lively, and even foolish; sometimes her ideas were incoherent, and she often indulged in tears.