In others the disorder was more perceptible. In a few hours the eyes became muddy, the surface of the body cold, with drowsiness, lethargy, and pain at the heart. In the progress of the distemper they frequently lost the power of speech, the skin seldom recovered its warmth, or, if it did, it was only by irregular flushings. The pulse sometimes remained nearly in its natural state, but was, for the most part, low and quick. They were “by turns delirious, confused and sensible, but the comatose disposition was most prevalent. Towards the end they suffered extreme inquietude. Vomiting in some occurred the first night; in others a diarrhœa next day; both accelerating the fatal period; but these symptoms were less frequent than in some of the other classes. Buboes appeared only in a very few who survived the third day.... The total absence of buboes in such patients as perished suddenly I have no doubt of, nor of their being in general very rare in others of this class; though I suspect that the buboes might sometimes have been concealed, where the disease ran out to the fourth or fifth day, and for the same reason that the reports concerning the state of the corpse were sometimes not true.... It was very rare to find suspicious marks of infection on the bodies [of those who died within 24 hours].... Carbuncles were seldom visible till the month of May, which was later than this form of the disease. It prevailed chiefly at the rise of the plague in 1760, and its revival in the two succeeding years, decreasing as the distemper spread; and though they were found dispersed in every stage of the pestilential season, yet the number of this class was proportionably small, compared with that of others. Petechiæ, vibices, or broad, livid, roundish spots, occurred sometimes, but were not common, and the two latter were seldom visible till after death.”