Family 4 (Pedigree Chart, No. K 6) illustrates the same kind of facts and conclusions. In the A Generation a Frenchman, whose eye-colour was unknown to my informant, married a full blood Indian princess who had Indian brown eyes. There was one daughter only (Generation B) by this marriage, and she had Indian brown eyes. She married an Irishman, who had red hair, grey eyes, and a freckled complexion (Generation B). From this marriage there came six children (Generation C). Two of these had "grey eyes like their father." Three had dark brown eyes of European tint. My informant had some doubt as to the European tint of two of these three (Nos. 3 and 4, C Generation); their eye-colour was very dark brown, and possibly it may have been the Indian tint. The remaining member of this generation had Indian brown eyes of a very dark shade. It may be desirable to state that Families 4 and 5 come from different parts of Canada. The chief feature of interest in this family is the segregation of the grey eye-colour of the Irishman among his offspring. It appears in two daughters. From what we know of analogous cases, there is little doubt that the gametes of his half-breed Indian wife carried the blue or grey factors derived from her French father. The appearance of an European brown eye-colour in Generation C, No. 6, suggests that the French grandfather had brown eyes, and that, therefore, this colour has segregated out among the gametes of the half-breed Indian mother. Exhibited by Mr. E. Nettleship. [Sidenote: L] [Sidenote: L 1] +Congenital Colour-blindness+. Pedigree showing unusual features, viz.: (_a_) females affected; (_b_) twins, of whom one is affected, the other not; (_c_) marriage between two unrelated colour-blind stocks. Except that two females are affected the inheritance, so far as can be traced, has followed the rule for colour-blindness; viz., limitation to males and transmission through unaffected females. _Key to Signs_. [M] normal male; [F] normal female. [M-] colour-blind male; [F-] colour-blind female. [circle] batch of whom there are no particulars. [OO with over bar] twins. [Greek: ph] died in infancy. [ob]: dead. [×] seen and examined. [× ×] reported normal, but not seen. [Sidenote: L 2] +Hereditary night-blindness with myopia+ (short sight) affecting 21 males and only 1 female in a large pedigree. The night-blindness congenital and stationary. Descent always through mothers themselves unaffected. Mental defects in several of the night-blind stock. Other pedigrees of this male-limited night-blindness are on record. _Key_. [M-] and [F-] night-blind male and female. Otherwise the same as for L 1. [Sidenote: L 3] Pedigrees of +hereditary congenital Nystagmus+ (involuntary rhythmical movements of the eyes) showing two different modes of descent. [Sidenote: L 3a] In Figure L 3a the nystagmus occurs only in males and descends through unaffected females. [Sidenote: L 3b]