Men may contract the particular and raging Symptom, which is very generally peculiar to this Disease from this Cause, and even without any Bite; but this happens very rarely indeed. It is properly a Distemper belonging to the canine _Genus_, consisting of the three Species of Dogs, Wolves, and Foxes, to whom only it seems inherent and natural; scarcely ever arising in other Animals, without its being inflicted by them. Whenever there occurs one of them who breeds it, he bites others, and thus the Poison, the Cause of this terrible Disease, is diffused. Other Animals besides the canine Species, and Men themselves being exposed to this Accident, do sometimes contract the Disease in all its Rage and Horror: though it is not to be supposed, that this is always an unfailing Consequence. Sec. 189. If a Dog who used to be lively and active, becomes all at once moapish and morose; if he has an Aversion to eat; a particular and unusual Look about his Eyes; a Restlessness, which appears from his continually running to and fro, we may be apprehensive he is likely to prove mad; at which very Instant he ought to be tied up securely, that it may be in our Power to destroy him as soon as the Distemper is evident. Perhaps it might be even still safer to kill him at once. Whenever the Malady is certain, the Symptoms heighten pretty soon. His Aversion to Food, but especially to Drink, grows stronger. He no longer seems to know his Master, the Sound of his Voice changes; he suffers no Person to handle or approach him; and bites those who attempt it. He quits his ordinary Habitation, marching on with his Head and his Tail hanging downwards; his Tongue lolling half out, and covered with Foam or Slaver, which indeed not seldom happens indifferently to all Dogs. Other Dogs scent him, not seldom at a considerable Distance, and fly him with an Air of Horror, which is a certain Indication of his Disease. Sometimes he contents himself with biting only those who happen to be near him: while at other Times becoming more enraged, he springs to the right and left on all Men and Animals about him. He hurries away with manifest Dread from whatever Waters occur to him: at length he falls down as spent and exhausted; sometimes he rises up again, and drags himself on for a little Time, commonly dying the third, or, at the latest, on the fourth Day after the manifest Appearance of the Disease, and sometimes even sooner.