[56] The Use of Opiates in this Disease undoubtedly requires no Small Consideration, the great _Sydenham_ himself not seeming always sufficiently guarded in the Exhibition of them; as far as Experience since his Day has enabled Physicians to judge of this Matter. In general our Author's Limitations of them seem very just; though we have seen a few clear Instances, in which a light Raving, which evidently arose from Want of Sleep (joined to some Dread of the Event of the Disease by Inoculation) was happily removed, with every other considerable Complaint, by a moderate Opiate. In sore and fretful Children too, under a large or middling Eruption, as the Time gained to Rest is taken from Pain, and from wasting their Spirits in Crying and Clamour, I have seen Suppuration very benignly promoted by _Diacodium_. But in the _Crisis_ of the secondary Fever in the confluent or coherent Pock, when there is a morbid Fulness, and Nature is struggling to unload herself by some other Outlets than those of the Skin, which now are totally obstructed (and which seems the only Evacuation, that is not restrained by Opiates) the giving and repeating them then, as has too often been practised, seems importantly erroneous; for I think Dr. _Swan_ has taken a judicious Liberty of dissenting from the great Author he translates, in forbidding an Opiate, if the Spitting abates, or grows so tough and ropy, as to endanger Suffocation. As the Difference of our Oeconomy in the Administration of Physic from that in _Swisserland_, and Dr. _Tissot's_ just Reputation may dispose many Country Practitioners to peruse this Treatise, I take the Liberty of referring such Readers, for a Recollection of some of my Sentiments of Opiates, long before the Appearance of this Work in French, to the second Edition of the Analysis from P. 94 to 97, _&c._ _K._ Sec. 218. If Eruption should suddenly retreat, or strike in, heating, soporific, spirituous and volatile Remedies should carefully be avoided: but the Patient may drink plentifully of the Infusion No. 12 pretty hot, and should be blistered on the fleshy Part of the Legs. This is a very embarrassing and difficult Case, and the different Circumstances attending it may require different Means and Applications, the Detail and Discussion of which are beyond my Plan here. Sometimes a single Bleeding has effectually recalled Eruption at once.