This horrible Evil however may be prevented by an Application to these small Tumours, as soon as ever they appear, For this Purpose nothing is more effectual than the Prescriptions No. 57 and 60; but under such menacing Circumstances, it is always prudent to take the best Advice, as early as possible. From the Moment these hard Tumours become excessively and obstinately so, and yet without any Pain, we should abstain from every Application, all are injurious; and greasy, sharp, resinous and spirituous ones speedily change the _Scirrhus_ into a Cancer. Whenever it becomes manifestly such, all Applications are also equally pernicious, except that of No. 60. Cancers have long been thought and found incurable; but within a few Years past some have been cured by the Remedy No. 57; which nevertheless is not infallible, though it should always be tried. [84] [84] The Use of Hemlock, which has been tried at _Lyons_, by all who have had cancerous Patients, having been given in very large Doses, has been attended with no Effect there, that merited the serious Attention of Practitioners. Many were careful to obtain the Extract from _Vienna_, and even to procure it from Dr. _Storck_ himself. But now it appears to have had so little Success, as to become entirely neglected. _E. L._ Having exactly translated in this Place, and in the Table of Remedies, our learned Author's considerable Recommendation of the Extract of Hemlock in Cancers, we think it but fair, on the other Hand, to publish this Note of his Editor's against it; that the real Efficacy or Inefficacy of this Medicine may at length be ascertained, on the most extensive Evidence and Experience. As far as my own Opportunities and Reflections, and the Experience of many others, have instructed me on this Subject, it appears clear to myself, that though the Consequences of it have not been constantly unsuccessful with us, yet its Successes have come very short of its Failures. Nevertheless, as in all such Cancers, every other internal Medicine almost universally fails, we think with Dr. _Tissot_ it should always be tried (from the meer Possibility of its succeeding in some particular Habit and Circumstances) at least till longer Experience shall finally determine against it. _K._ Sec. 376. The Nipples of Women, who give Milk, are often fretted or excoriated, which proves very severely painful to them. One of the best Applications is the most simple Ointment, being a Mixture of Oil and Wax melted together; or the Ointment No. 66. Should the Complaint prove very obstinate, the Nurse ought to be purged, which generally removes it. __Chapter XXVII.__ _Medical Directions concerning Children._ __Sect.__ 377.