Aids to Forensic Medicine and ToxicologyRobertson, W. G. Aitchison (William George Aitchison )
Science
Aids to Forensic Medicine and Toxicology
Robertson, W. G. Aitchison (William George Aitchison )
Medical jurisprudence; Poisons
_Symptoms._--The symptoms usually come on in a few seconds, and are of
the shortest possible duration. There is a sudden gasp for breath,
possibly a loud cry, and the patient drops down dead. If the fatal
termination is prolonged for a few minutes, the symptoms are intense
giddiness, pallor of the skin, dilatation of the pupils, laboured and
irregular breathing, small and frequent pulse, followed by
insensibility. There may be convulsions or tetanic spasms, with
evacuation of urine and faeces. Death results from paralysis of the
central nervous system, but artificial respiration is useless, as the
drug promptly arrests the heart's action. It also kills the protoplasm
of the red blood-corpuscles, rendering them useless as oxygen-carriers.
_Post-Mortem Appearances._--Skin livid, pale, or violet, with bright red
patches on the dependent parts. The gastro-intestinal mucous membrane is
bright red in colour, owing to the presence of cyanmethaemoglobin. Hands
clenched, nails blue, jaws fixed, froth about mouth. Eyes prominent and
glistening, odour of acid from body, venous system gorged.
_Treatment._--Empty the stomach by the tube at once, and wash it out
with a solution of sodium thiosulphate. Strong ammonia to the nostrils.
Stimulants freely--brandy, chloric ether, ammonia, sal volatile _ad
libitum_. If patient cannot swallow, inject hypodermically either brandy
or ether. Hypodermic injection of 1/50 grain atropine. Douche to the
face, alternately hot and cold. Death commonly occurs so rapidly that
there is no time for treatment.
_Fatal Dose (Smallest)._--Half a drachm of the B.P. acid, equal to 0.6
grain of the anhydrous. _Recovery_ from 1/2 ounce of the B.P. acid.
These records are fallacious, for in specimens the percentage of
anhydrous acid varies enormously. Practically, 1 grain of the anhydrous
acid is fatal.
_Fatal Period._--From two to five minutes after a large dose, but may be
less.
_Method of Extraction from the Stomach._--Having previously carefully
fitted a watchglass to a wide-mouthed bottle, nearly fill the bottle
with the contents of the stomach, blood, secretions, etc. Place a few
drops of a solution of nitrate of silver on the concave surface of the
watchglass, and cover the mouth of the bottle with it. The vapour of
hydrocyanic acid, if present, will form a white precipitate which may be
tested. Other watchglasses, treated with sulphide of ammonium or
sulphate of iron and liquor potassae, will give the reactions of the acid
with appropriate tests. This method removes all objections as to foreign
admixture. If the acid is not at first detected, gentle warming of the
bottle in a water-bath will assist the evolution of the vapour. The
vapour may be obtained by distillation, but this process is open to
objections to which the other is not. In some cases it becomes changed
in the body into formic acid, which should therefore be sought for.
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